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Case Center For Imaging Research

Small Animal Imaging

 
 
Case Western Reserve University and University Hospitals Health System

 

Bioluminescense (BLI)

The Xenogen IVIS Imaging 200 Series system allows researchers to use real-time, non-invasive imaging to monitor and record cellular and genetic activity in vivo. Integrated into the system are both a bioluminescence system and a fluorescence system and the capability to easily switch between modalities. A laser scanner also provides 3D surface topography for single-view diffuse tomographic reconstructions of internal sources. Background noise is minimized while sensitivity is maximized using a 26 mm square CCD which is cryogenically cooled. An anesthetic system is built-in to keep animals anesthetized for the duration of the experiment. Scans generally take 1-10 minutes to complete with five field of view options ranging from 4 cm to 25 cm.

Sample Image:

 


For more information, see the manufacturer's website.